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ConcernsPsychosis

Psychosis

Psychosis means hallucinations, delusions and disordered thinking. Signs of psychosis, its causes, and how first episode psychosis is treated in the UK.

Clinical review: pending
NICE guidance: CG178

Psychosis is a set of experiences in which a person perceives or interprets things differently from those around them: hallucinations, delusions, and confused or disorganised thinking. Psychosis is not a diagnosis in itself. It occurs in several mental health conditions, and also in physical illness, brain injury and drug use.

Key points

  • Psychosis is a set of experiences, not a diagnosis in itself. It occurs in several mental health conditions, and in physical illness, brain injury and drug use.
  • The main experiences are hallucinations, delusions and disorganised thinking.
  • People experiencing psychosis are far more likely to be harmed than to harm anyone else.
  • In England, Early Intervention in Psychosis treatment should start within two weeks of referral.
  • NICE recommends antipsychotic medication and psychological therapy together, not medication alone.

Symptoms

  • Hearing, seeing or feeling things other people do not (hallucinations).
  • Strongly held beliefs others do not share, which do not shift with evidence against them (delusions).
  • Speech that is fast, jumps between subjects or stops suddenly, and trouble concentrating.

Causes and risk factors

  • Family history of psychosis or schizophrenia; raised dopamine activity in the brain.
  • Cannabis: across Europe, daily use was associated with around three times the odds of a psychotic disorder, daily high-potency cannabis with around five times.
  • Severe stress, anxiety, depression and prolonged sleep loss can all trigger episodes.

Treatment

  • First episode: oral antipsychotic medication together with psychological therapy through an Early Intervention in Psychosis service.
  • Cognitive behavioural therapy for psychosis (CBTp), at least 16 planned sessions.
  • Family intervention, at least 10 planned sessions over three months to a year.

When to speak to a professional

  • Hearing, seeing or feeling things other people do not; holding a belief others do not share that does not shift when questioned.
  • Becoming hard to follow in conversation, or withdrawing sharply and no longer managing work, food or washing.
  • Use the word psychosis and ask for an urgent referral to Early Intervention in Psychosis - getting in quickly matters.
If you need help now: Samaritans, call 116 123, free, 24/7. Shout, text SHOUT to 85258. NHS 111, then choose the mental health option. Call 999 if anyone is in immediate danger.

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